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Beta-Amyloid (1-42), Ultra Pure β淀粉样肽(1-42),超纯,现货供应!



Product Name:   Beta-Amyloid (1-42), Ultra Pure
Catalog #:       P2000022
Storage:        -20°
Molecular Mass:  4514.1 4
Peptide Purity:  >98% 
Counter Ion:     HFIP treated 
Supplied As:     No salt, as HFIP desalts the sample.  
Source:   
Recombinant. A DNA sequence encoding the human beta-amyloid  (1-42)sequence was expressed in E. coli.  
 
Sequence:   
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala- Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala 
 
Resuspension:    
 
Resuspend  in 1 % NH4OH, at a concentration of 1 mg/ml. Sonicate for 30 seconds to 1 minute after it has gone into solution.  
     To bring it into your buffer: After resuspension, add 5x or 10x buffer stock and water, to bring to 1x buffer. 
 
Description:   
Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of  Alzheimer’s Disease (AD)1-3. AD is the most common neurodegenerative disease and afflicts about 10% of the population over 60 4. The abeta,HFIP is described in Stine, et. al.3.
1) Yankner, BA, et. al., (1990) Science, 250: 279-282 
2) Selkoe, D.J., (2001) Physiol. Rev, 81: 741-766    
3) Stine, W.B. et. al., (2003) J. Biol. Chem, 278: 11612-11622
4) Frank, R.A., et. al., (2003) Neurobiology of Aging, 24: 521-536  

HPLC REPORT: 
Product Name:    Beta-Amyloid(1-42), HFIP
Column:                4.6*250mm, SP-300-5-C4-BIO
Solvent A:              0.1%Trifluoroacetic in 100% Acetonirile
Solvent B:              0.1%Trifluoroacetic in 100% Water
Gradient:                                A                               B
                    0.01min            10%                         90%
                       25min           100%                         0%
                    25.1min           100%                         0%
                       30min                             Stop
Flow rate:              1.0ml/min
Wavelength:         220nm
 
Rank Time Name Conc. Area
1 8.000   0.319 4914
2 9.959   1.071 16490
3 10.519   98.23 1514485
4 11.018   0.2791 4298
Total     100 1540187

   
P2000022; Beta Amyloid 1-42

 

PLlabs其他产品:
β淀粉样肽(1-40),超纯,TFABeta-Amyloid (1-40), Ultra Pure, TFA
β淀粉样肽(1-40),超纯,HFIPBeta-Amyloid (1-40), Ultra Pure, HFIP
β淀粉样肽(1-40),超纯,NaOHBeta-Amyloid (1-40), Ultra Pure, NaOH
β淀粉样肽(1-40),超纯,HClBeta-Amyloid (1-40), Ultra Pure, HCl
β淀粉样肽(1-42),超纯,TFABeta-Amyloid (1-42), Ultra Pure, TFA
β淀粉样肽(1-42),超纯,HFIPBeta-Amyloid (1-42), Ultra Pure, HFIP
β淀粉样肽(1-42),超纯,NaOHBeta-Amyloid (1-42), Ultra Pure, NaOH
β淀粉样肽(1-42),超纯,HClBeta-Amyloid (1-42), Ultra Pure, HCl

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